Daniel W. Rosenberg has more than 25 years of experience in the field of cancer biology using mouse models and human biospecimens. He is presently an Investigator in the Center for Molecular Medicine at the University of Connecticut Health Center, directing an active research program that focuses on Colorectal Cancer and Chemoprevention.
He has established a translational research program in Cancer Prevention that is formally associated with the Neag Cancer Center and serves as the Program Director. The research focus of the Program covers several areas of colon cancer biology, with translational applications in prevention and early detection, as well as therapeutic interventions.
He has published several recent papers that identify early molecular signatures of hyperplastic lesions in the distal colon in biospecimens obtained from screening colonoscopy patients. He is actively studying the association of cigarette smoking with the development of a subset of colorectal cancers that display a distinct spectrum of histological and molecular features. He has assembled an experienced and integrated group of investigators, both clinicians and basic researchers, with demonstrated expertise in various aspects of colon cancer screening, development of biomarkers and cancer pathogenesis.