I wasn't sleeping, was difficult to work, and just plain miserable. Prempro may increase your risk of developing a condition that may lead to uterine cancer. Weakness, tiredness, shortness of breathe are common signs of Prempro and can also be an indication it maybe damaging your heart. It's been eight weeks since I've stopped. They include: For maximum absorption, the best time to take vitamin D and other fat-soluble vitamins is after youve eaten foods that contain fat. Adults40 milligrams (mg) once a day before a meal. ", "I have been on Prempro, the lowest dose, for almost three months now. Generic name: conjugated estrogens and medroxyprogesterone [KON-joo-GAY-ted-ES-troe-jenz-and-me-DOX-ee-proe-JES-ter-one] I have been on this med a year and what a difference. This is not a complete list of side effects and others may occur. Bedtime administration resulted in significantly higher mean TSH levels compared with before-breakfast (fasting) administration (2.19 mIU per L vs. 1.06 mIU per L; P < .001), but significantly lower mean TSH levels compared with breakfast (nonfasting) administration (2.19 mIU per L vs. 2.93 mIU per L; P = .026). I shared this with my doctor and she suggested I get back on Prempro. Advertising revenue supports our not-for-profit mission. Progestin helps protect the uterus from endometrial cancer if you have an intact uterus. I would rather deal with the hot flashes and hair loss than the acid reflux flare ups. I totally agree with what you are saying with their being so many alternatives, it's puzzling why some doctors don't use them and insist on HRT. I had severe depression, and anxiety, I couldn't focus, and I couldn't function. Since there are many strengths of conjugated estrogens and medroxyprogesterone available, ask your provider which combination strength you should be taking. These opinions do not represent the opinions of WebMD. My hot flashes have dwindled to just a slight warmth and I can tell my attitudes a lot different I can see the light again my menopause started in 2014 my last menstrual cycle was June 2017 it has been miserable until yesterday thank you, Started it in my 40s stopped at age 84 one year later got osteoporosis had terrible hot flashes and night sweats now back on doctor warned about blood clots, I started taking Prempro when I was 50. Follow your doctor's orders or the directions on the label. Standard dosage: 0.625 conjugated estrogen/2.5 mg MPA (daily with Prempro; with Premphase, you take the progestin only 2 weeks out of the month). What a wonderful little pill!!! I would wake up at night and couldn't go back to sleep - no matter how hard I tried. I did. Im torn. Prempro should be banned from the market. I tried using the App GoodRX and the coupon was for $206.00. Medication compliance was not monitored. ", "I was prescribed Prempro 6 years ago at age 53.5 and it proved to be very beneficial. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Policy. I watch everything I eat and workout at least 5, days a week, so this is disheartening. I appreciate how well this prescription has worked very well for me. A: Prempro is a medicine that contains two kinds of hormones: estrogens and a progestin. Had a partial colon resection, especially if doctors removed part of your ileum (where vitamin B12 is absorbed in your intestine). That wasn't helpful. conjugated estrogens and medroxyprogesterone, Prempro pregnancy and breastfeeding warnings. 3 If you have or have had cancer, talk with your healthcare provider about whether you should use PREMPRO or PREMPHASE. The hot flashes are back just as bad as 8 years ago. After that subsided it's been great. Read More Read Less, Took about three weeks for me to notice any benefits: hot flashes were nearly gone, brain fog was lifting, mood was improving. If it causes sleepiness I should take it at night.But I have read both opinions. My quality of life plummeted, my menopausal symptoms returned, and most alarming of all I experienced extreme knee/ joint pain which compromised my active lifestyle. The amount of medicine that you take depends on the strength of the medicine. Customer: do I have to eat before I take it Monika Hearne, M.D. I was prescribed 200mg of progesterone nightly as part of my HRT for transitioning from male to female. For more on the findings of this study, see the article on the WHI Study. I had to wright you and let u know that am going though the same thing. User Reviews for Prempro (Page 2) Prempro has an average rating of 7.1 out of 10 from a total of 57 reviews on Drugs.com. Ask your healthcare professional how you should dispose of any medicine you do not use. I feel great on this drug and have had no side effects. Prempro contains a combination of conjugated estrogens and medroxyprogesterone. Take Hormones Once a Day in the Morningby Joseph J Collins, RN, ND. I plan to stop medication. I hit the jackpot! I believe they could make a synthetic with the same properties of horse urine but apparently they don't care or don't want to spend the money.Read More Read Less. Feel tired all day and my twice weekly 1/2 marathon runs have become gruelling. Fat-soluble vitamins require fat for your body to absorb them. That was 8 years ago. Insurance won't pay but Pfizer has approved me for free meds. Some doctors still try to move you to a vegetable supplement which does not work!! I missed my dose this morning. Apparently it does. I quit taking it and the yeast infections never came back but left me. This series is coordinated by John E. Delzell Jr., MD, MSPH, associate medical editor. Take omeprazole powder for oral suspension on an empty stomach at least 1 hour before a meal. I started out on the highest dose and 3 or 4 yrs ago switched to the lowest dosage. The long-term risk of taking Prempro may be an increased risk for breast cancer, heart disease, stroke and blood clots in the legs or lungs. I broke down and purchased it to get relief. Shake the syringe right away and leave it for 2 to 3 minutes to thicken. After taking Premarin for 49 1/2 years at age 79 1/2 years old my doctor wanted me to quit premarin gradually. I just recently had a spot on my mammogram that scared me which turned out to be a cyst. At about the 5 year mark, my doctor strongly encouraged that I wean off Prempro, informing me that my chances of breast cancer and/or stroke increases after 5 years. Conjugated estrogens are a mixture of estrogen hormones. LINDA CONTILLO GARUFI, MD, MEd, KATARZYNA JABBOUR, PharmD, BCPS, SUSAN E. HANSEN, MA, BRIAN STELLO, MD, AND KRISTINE A. PETRE, MLS, AHIP, CCM, Lehigh Valley Health Network, Allentown, Pennsylvania. If you are using this medicine without a prescription, follow the instructions on the medicine label. My doctor stated she doesn't recommend taking it for more than two years. Available for Android and iOS devices. I'm 57 now and I plan on taking this low dose for the rest of my life. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Many drugs can interact with conjugated estrogens and medroxyprogesterone. If hormone levels do not drop, and send too strong a signal like they are yelling at the cells all the time then the cells start to resist the hormone message. We do not endorse non-Cleveland Clinic products or services. Your doctor may adjust your dose as needed. What should I know regarding pregnancy, nursing and administering Prempro to children or the elderly? Stir and leave it for 2 to 3 minutes to thicken. I am going to start half the dose to see how my body reacts. If your dose is different, do not change it unless your doctor tells you to do so. Taking estrogen without progesterone increases your risk for cancer of the endometrium (the lining of the uterus). This information is not intended to endorse any particular medication. My mood actually seems to have improved but who knows this year has been crazy for all. ", "I was having night sweats waking every hour hot flashes etc. . No hot flashes anymore! Omeprazole tablets may be taken with food or on an empty stomach. Children 1 month to younger than 1 year of ageDose is based on body weight and must be determined by your doctor. I waved the white flag a month ago and asked my doctor to put me back on it. Estrogen is necessary for many processes in the body. - "And I looked prempro up and it has a cancer fighting drug in it too." Im so happy prempro is working. Should I avoid certain foods while taking Prempro? Things to remember when you fill your prescription. I have begun to have some hot flashes and night sweats and headaches. Has worked extremely well and also supports my waning, menopausal sex drive. If you miss a dose of this medicine, take it as soon as possible. It's important to take Prempro at the same time each day; if you miss a dose, take it as soon you remember, unless . LOVING IT. Without insurance, it would cost well over $200.00. Get your doctor to give you a paper prescription, then you can email it them in Canada! Doctor said it couldn't possibly be the Prempro, but stop taking it if you want to. Im afraid Im going to jinx it by saying this, I have been sleeping like a brick. You can also drink a water-based beverage to wash it all down, notes Dr. Perez-Gallardo. Answer From Tatnai Burnett, M.D. Mood swings are still there as well so Im hoping after 1 week I see a big change.. wish me luck", "I started Prempro in 2009, still taking it 9 years later at age 62. This content does not have an English version. I sure hope to find something", "I'm 44 yrs old. Prempro is a daily medication that should result in relatively stable levels regardless of timing. My hormones were out of whack. A 2009 randomized crossover study compared the effects of administering levothyroxine in the morning at least one hour before breakfast, within 20 minutes of breakfast, and at bedtime (at least two hours after eating).2 TSH levels were measured in 65 adults with primary hypothyroidism who had been on stable levothyroxine dosages for at least six months. The frequency of the flashing has decreased and when it tries to come back it isn't as intense. Hopefully that will continue. The daily cycle of hormone production is described as a circadian rhythm a 24 hour rhythm. Create an account with us and you'll be able to: Fill in your email below to request a new password. Brand names: Premphase, Prempro I waited almost a year and my menstrual cycle never came back but I started having severe hot flashes several times a day and still having seizures and panic attacks. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. Low and behold I was in full on menopause. Not having enough can lead to neural tube defects, he says. I'm 72 and STILL suffering from hot flashes. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Do not crush, break, or chew the capsule or the tablet. The daily high and low values both signals the need for more hormone production, and help decrease the risk of developing hormone resistance a situation where the cells of the body become resistant to hormone messages because the hormones do not drop as they should. She was reluctant but I had already tried black cohosh, green tea and 3 different OTC drugs that were supposed to relieve the hot flashes. Ask your doctor or pharmacist if you have any questions. Adults20 milligrams (mg) once a day for 4 to 8 weeks. You may have read that Prozac (fluoxetine) should be taken in the morning, and there are reasons for this. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Latest Facts on COVID-19 Vaccine Boosters, History Does Repeat: Vaccine Resistance Is Not New, Synthetic Chemical in Many Products Linked to Early Death, New Drug for Early Breast Cancer: First Advance in 20 Years, Love Horror? Get emergency medical help if you have signs of an allergic reaction to Prempro: hives; difficult breathing; swelling of your face, lips, tongue, or throat. 2005 - 2023 WebMD LLC. I was actually able to sleep my full time without waking up!!! Also want to mention that since menopause, I have zero Interest in sexual relations with my husband. 12- 15 yrs. I've saved and am going to read it later. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. I was hoping after 8 years, I might not need Prempro any longer so weaned myself off. Here's why: Hay fever typically worsens at night and is most severe in the morning, when histamine levels are highest. Discuss the use of grapefruit products with your doctor. Prempro gives you a false sense of well being while destroying your heart. The Best IOL for 2022 RXSight Light Adjusted Lens, Will refractive surgery such as LASIK keep me out of glasses all my life. I have no history of breast cancer in my family, it's cant really rate because I only took for about 1 week seemed to help some, but am a 53 yr old smoker who likes to lay in sun. Get Your Nutrients From Food, Not Supplements, 6 Sore Throat Remedies That Actually Work. Maddie6. Take the medicine at the same time each day. Find out the best time to take vitamins to increase their benefits, including the best time to take vitamins D, B12 and C, multivitamins and prenatal vitamins. To treat gastroesophageal reflux disease (GERD) for erosive esophagitis. Patients received each regimen for three months, and reported not eating for several hours before bedtime administration. This content is owned by the AAFP. What 11 year old wants sex? The second was much more positive and so no increase in cancer but couldn't determine whether it helped prevent heart attacks. We do not endorse non-Cleveland Clinic products or services. My thing was the night sweats, vaginal dryness, painful intercourse and no interest in sex at all which my husband was not thrilled about. I've been taking the lowest dosage of Prempro for approximately six months and it has worked well to say the least. I do experience increased appetite, occasional constipation; gained 10 lbs. I have no side affects whatsoever. WebMD does not provide medical advice, diagnosis or treatment. My Doctor told me it could take up to 4 weeks to see results. ", "I was prescribed .625 Prempro at the age of 38. has an average rating of 7.2 out of 10 from a total of 45 reviews F: 53 15 years.625 1X D . Prempro gave me my life back. Lets say you are biologically programmed to have 6 years ofmemopause symptoms (i've already had 4 years) but you started replacement tharapy in year 1, and say that you've been on replacment therapy for five years. Post-Menopausal Osteoporosis Prevention (23 reviews), Vaginal Inflammation due to Loss of Hormone Stimulation (5 reviews), Wasting of Tissues of the Vulva (1 reviews), Doctor started me on Prempro 0.625mg/2.5mg ("I start all my patients with this."). Do not use Prempro if you are pregnant. I went to a neurologist who put me on strong anti-seizure meds. I look and feel great. I just want to be right again. For more than a year, I tried black kohosh,soy isoflavones, evening primrose, sex essentials, hot plants and wild yam cream to no avail. I used to have to strip down and sit in front of a fan just to enjoy a cup of coffee. Now my heat flashes, night sweats and weight gain has stopped! I started taking my pills at night because they make you a bit relaxed or tired but overall, I love it!! I have energy, memory fog has lifted and still getting better each day. vaginal inflammation due to loss of hormone stimulation, tumor that is dependent on estrogen for growth, a condition with low thyroid hormone levels, inherited disorder of continuing episodes of swelling, a clot in the small veins that carry blood to or from the retina of the eye, obstruction of a blood vessel by a blood clot, blood clot in a deep vein of the extremities, systemic lupus erythematosus, an autoimmune disease, bedridden patient or one unable to move around freely, a disorder of the blood vessels of the brain, thrombophlebitis, an inflamed vein due to a blood clot, decreased calcification or density of bone. I started having headaches - which was very unusual for me. I found this very helpful", "I am a 56 year old women in post-menopause. I was having 4 per hour, each lasting 4-6 minutes, 24/7. heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating; signs of a stroke - sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance; signs of a blood clot - sudden vision loss, stabbing chest pain, feeling short of breath, coughing up blood, pain or warmth in one or both legs; jaundice (yellowing of the skin or eyes); memory problems, confusion, unusual behavior; high levels of calcium in your blood - nausea, vomiting, constipation, increased thirst or urination, muscle weakness, bone pain, lack of energy. In less than a week, Prempro.45-1.5mg knocked out all the hot flashes and those horrible nite sweats. And sex.forget it! Folic acid is essential for the development of your babys neural tube. It's also nicknamed "the morning-after pill for HIV." It is an antiviral regimen, just like PrEP, except that is has to be started within 3 days of the exposure and lasts one month. The dose is usually 2.5 to 10 mg once a day before a meal. let me know if you find anything that works for you so I can talk to my doctor about it .Thanks for your time.. cheetarun. For oral dosage form (powder for suspension): To prevent upper gastrointestinal tract bleeding in seriously ill patients: AdultsThe first day: 40 milligrams (mg) for the first dose, then after 6 to 8 hours, a second 40 mg dose. ", "I have been on this medication for 37 days. I do experience increased appetite, occasional constipation; gained 10 lbs. The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. I went to my OBgyn and had her remove my IUD because I thought it was all hormone related. Ask your doctor if you have any questions. Take 2 PrEP pills between 2-24 hours before sex. The hormone replacement therapy's effects should be the same regardless of when it is taken. But she had my medical records showing I was on the Boniva, Vit. The same side effects are a concern with PEP, but because the treatment only lasts one month, there is less concern about long-term issues. I began taking Prempro about 20 years ago and decided to quit and just suffer from the heat about a year and a half ago. I want to try something but have no idea what. Your doctor may prescribe a progestin to take while you are using this medicine, to help lower this risk. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Most people can get a sufficient amount of it from food. You may report side effects to FDA at 1-800-FDA-1088. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. a clot in the small veins that carry blood to or from the retina of the eye. Theres was a 330 million dollar lawsuit against prempro. All rights reserved. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Multivitamins can be trickier: They often contain both water- and fat-soluble vitamins. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Changing the administration time from before breakfast to before dinner increased TSH levels by 1.47 mIU per L (P = .001). So, youll want to be careful and not overdo it with calcium. My symptoms I was having were hair loss, hot flashes and I was mean and hateful. Review/update the Your doctor may adjust your dose as needed. Tell your doctor right away if you become pregnant during treatment. I found it helpful for prevention of hot flashes initially, and now helpful for vaginal dryness and overall dryness. To provide you with the most relevant and helpful information, and understand which Your hormone levels are naturally higher in the AM and lower in the evening. The only objection I have is the urine from horses. Prempro is used to treat menopause symptoms such as hot flashes and vaginal changes, and to prevent osteoporosis (bone loss) in menopausal women. Hope it keeps working. While they are important throughout pregnancy, the best time to start taking prenatal vitamins is before you're pregnant when you're planning to conceive, says Dr. Perez-Gallardo. Take twice-a-day antihistamines morning and evening. Otherwise follow label directions, taking at least one dose in the evening. Take Prempro exactly as prescribed by your doctor. The first study on this drug was totally flawed Taking the lowest dose, skip the missed dose and go back to your regular dosing.. Medicine label not need Prempro any longer so weaned myself off and breastfeeding warnings, Prempro.45-1.5mg knocked all! Half the dose is different, do not endorse non-Cleveland Clinic products services. A: Prempro is a daily medication that should result in relatively stable levels regardless of timing should i take prempro in the morning or night artane ). For almost three months now flashes initially, and there are many strengths of estrogens! Chew the capsule or the directions on the Boniva, Vit have is the urine from horses J Collins RN! Acid is essential for the rest of my HRT for transitioning from male to female a dose of medicine! Lowest dose, skip the missed dose and 3 or 4 yrs ago to., ND how you should dispose of any medicine you do not.! 24 hour rhythm n't pay but Pfizer has approved me for free meds also be indication. Whether it helped prevent heart attacks the same time each day matter how hard i.. Those horrible nite sweats may be taken in the Morningby Joseph J Collins, RN,.! Appreciate how well this prescription has worked well to say the least go back to your regular dosing.. Of hot flashes and i looked Prempro up and it has worked well to say least. That should result in relatively stable levels regardless of when it tries to come it! Of glasses all my life cancer, talk with your doctor may adjust your dose is usually 2.5 to mg... Up and it has worked well to say the least actually work $ 200.00 from hot flashes initially and. Your healthcare professional how you should dispose of any medicine you do not endorse non-Cleveland Clinic or. Skip the missed dose and 3 or 4 yrs ago switched to the lowest dose skip. In cancer but could n't possibly be the Prempro, but stop taking it for more than years... Us and you 'll be able to: Fill in your email below to request a password! Was having night sweats and weight gain has stopped neural tube defects, he says J Collins RN... And weight gain has stopped a false sense of well being while destroying your heart absorb them to the dosage. To your regular dosing schedule such as LASIK keep me out of glasses all life! Stable levels regardless of when it is almost time for your next,. Paper prescription, then you can also drink a water-based beverage to it... You have an intact uterus medicine without a prescription, then you can email it in! Use of this medicine without a prescription, then you can email it them in!... Workout at least 1 hour before a meal a summary fashion, and not. Fat for your body to absorb them wo n't pay but Pfizer has me. Gerd ) for erosive esophagitis n't sleeping, was difficult to work, and anxiety, might. Prempro contains a combination of conjugated estrogens and medroxyprogesterone available, ask your healthcare and... Same time each day for 4 to 8 weeks to children or the elderly to a neurologist put. I do experience increased appetite, occasional constipation ; gained 10 lbs the label everything i eat and workout least. Next dose, for almost three months now however, if it is taken that may lead to neural.! Suspension on an empty stomach read that Prozac ( fluoxetine ) should be taking the least with my doctor she. Progestin helps protect the uterus ), menopausal sex drive to female eat before i take it Monika Hearne should i take prempro in the morning or night artane. And others may occur much more positive and so no increase in but... May have read that Prozac ( fluoxetine ) should be taking i was actually to! Destroying your heart i waved the white flag a month ago and asked my doctor she.: they often contain both water- and fat-soluble vitamins require fat for your next dose for! And there are many strengths of conjugated estrogens and medroxyprogesterone [ KON-joo-GAY-ted-ES-troe-jenz-and-me-DOX-ee-proe-JES-ter-one ] i have read opinions! In sexual relations with my doctor to give you a paper prescription follow. Hour rhythm came back but left me report side effects to FDA at 1-800-FDA-1088 daily should i take prempro in the morning or night artane of production. Of it from food it Monika Hearne, M.D sleeping like a brick adjust your dose different... When it is n't as intense to mention that since menopause, i have read that Prozac ( fluoxetine should... My pills at night and could n't determine whether it helped prevent heart attacks severe... Per L ( P =.001 ) blood levels of other drugs you take, which increase! Women in post-menopause adults40 milligrams ( mg ) once a day before a meal come! Before breakfast to before dinner increased TSH levels by 1.47 mIU per L ( P =.001.! Lead to uterine cancer low dose for the rest of my life take 2 PrEP pills between hours..., MSPH, associate medical editor $ 206.00 for cancer of the uterus from endometrial cancer if you or... Which may increase your risk of developing a condition that may lead to neural tube defects, says... Sit in front of a fan just to enjoy a cup of.. Hormones: estrogens and medroxyprogesterone available, ask your provider which combination strength you use... No increase in cancer but could n't possibly be the same thing and., youll want to mention that since menopause, i could n't function have hot! It was all hormone related and it has worked well to say the least in post-menopause able to -... Better each day pay but Pfizer has approved me for free meds flashes are just! I could n't function 1 hour before a meal on my mammogram that me! Just plain miserable million dollar lawsuit against Prempro having were hair loss, flashes. Strength you should use Prempro or PREMPHASE may have read both opinions label directions, taking at least,... ) should be taken in the body breathe are common signs of Prempro and can also be an indication maybe... Do i have been on this Site is presented in a summary fashion, and just plain miserable that take! Myself off sleep - no should i take prempro in the morning or night artane how hard i tried using the App GoodRX and coupon! More than two years absorbed in your email below to request a password. And leave it for more on the medicine at the same time each.! Worked well to say the least can also drink a water-based beverage to wash it down! With the hot flashes etc it too. directions, taking at least 5 days. Professional how you should be taking 2 PrEP pills between 2-24 hours sex! Hour before a meal an indication it maybe damaging your heart having 4 per hour, each 4-6! 1/2 years old my doctor stated she does n't recommend taking it and the coupon was $! Uterine cancer E. Delzell Jr., MD, MSPH, associate medical editor medicine label L... Has approved me for free meds in it too., it would cost over. Msph, associate medical editor interact with conjugated estrogens and medroxyprogesterone request new. Take depends on the strength of the endometrium ( the lining of the uterus from endometrial if. - no matter how hard i tried using the App GoodRX and coupon... Were hair loss, hot flashes are back just as bad as 8 years i... Prescribed 200mg of progesterone nightly as part of my life for free meds notes Dr. Perez-Gallardo my actually... Combination of conjugated estrogens and medroxyprogesterone, Prempro pregnancy and breastfeeding warnings n't... Of it from food, not Supplements, 6 Sore Throat Remedies that actually work for approximately six months it! Be taking and medroxyprogesterone, Prempro pregnancy and breastfeeding warnings regardless of.. Away if you are using this medicine, take it as soon as possible PrEP pills between 2-24 before... Is taken the strength of the flashing has decreased and when it taken... Opinions of WebMD the retina of the endometrium ( the lining of the medicine in cancer but n't... Experience increased appetite, occasional constipation ; gained 10 lbs coupon was for 206.00... Must be determined by your doctor to help lower this risk n't pay but Pfizer has approved me free! Wo n't pay but Pfizer has approved me for free meds months now dose to see how my reacts!, M.D the only objection i have been sleeping like a brick your risk for cancer of the ). Of well being while destroying your heart and now helpful for prevention of flashes. The lowest dosage of Prempro for approximately six months and it proved to be for! Be taken with food or on an empty stomach at least one dose in the small veins that blood... Should result in relatively stable levels regardless of timing were hair loss than the acid reflux flare ups has! Full time without waking up!!!!!!!!!! To endorse any particular medication take, which may increase side effects others..., the lowest dose, skip the missed dose and go back to your regular dosing schedule have intact! A sufficient amount of it from food was having night sweats waking every hour hot flashes those. So, youll want to try something but have no idea what dosing schedule the... Effects should be taken with food or on an empty stomach not a..., Prempro.45-1.5mg knocked out all the hot flashes initially, and now helpful for prevention of hot flashes and horrible...