Rosalia C.M. Simmen, PhD

Rosalia (Rosie) C.M. Simmen, PhD

Rosie Simmen is Professor, University of Arkansas for Medical Sciences and Senior Investigator in Developmental Biology, Arkansas Children’s Nutrition Center (Little Rock, AR). She completed her doctoral studies in Biochemistry at the University of Hawaii under the mentorship of Drs. Fred and Gillian Greenwood and her postdoctoral training in Molecular and Cell Biology was obtained at Baylor College of Medicine with Dr. Anthony Means as mentor. Her research interests focus on women’s health. As an independent investigator over the last 25 years, she has conducted studies on the biology of female reproductive tissues (uterus and mammary gland), with emphasis on mechanisms that regulate their normal biology and pathobiology. Currently, her laboratory studies how early ‘nutritional’ experiences influence the development of chronic diseases, specifically breast cancer, using rodent models of the disease. These investigations center on the effects of in utero, postnatal and early pubertal exposure to foods with recognized health benefits, including berries, and associated bioactive components on carcinogenesis and chemoprevention. Functional outcomes investigated include metabolic parameters, stem cells and their biology and transcriptional signatures. 

Dr. Simmen is the author of more than 150 peer-reviewed publications and book chapters. She serves (has served) on the Editorial Boards of Endocrinology, Biology of Reproduction, Journal of Endocrinology and Journal of Molecular Endocrinology and on multiple NIH and USDA Study Sections. Funding for research in her laboratory comes from the USDA (through the Arkansas Children’s Nutrition Center), NIH, and the Department of Defense Breast Cancer Research Program. She enjoys the opportunity to provide training and mentorship to undergraduate and pre-doctoral students, post-doctoral fellows, and junior faculty as well as productive research collaborations with many wonderful colleagues.