2017 Presentation Title – Consumption of Red Raspberries, at Typical Levels of Intake Reduces Metabolic Syndrome Parameters in High-fat Fed Mice

Ting Luo, a PhD candidate in the Food Science and Technology Department at Oregon State University. Her major advisor is Dr. Neil F. Shay, and their collaborative research is focused on the consumption of whole foods and specific phytochemicals and the remediation of metabolic syndrome symptoms. In particular, the approach utilizes a mouse model in which animals are fed a high-saturated fat diet with added cholesterol and sugar to model the Western diet, contributing to the development of obesity, diabetes, and other symptoms of metabolic syndrome. Additionally, their research examines gene- phytochemical interactions and includes metabolomics approaches.

Ms. Luo received her master’s degree at the State Key Laboratory of Food Science and Technology, Nanchang University in China, one of China’s top programs in Food Science and Nutrition. Her previous research explored the effects of dietary lipids on the occurrence of atherosclerosis; more specifically, the impact of triolein and trilinolein on oxidized low-density lipoprotein-induced oxidative stress in endothelial cells. She is an active member of the American Society for Nutrition, and the American Chemical Society, and has received a graduate student research award from ASN and a teaching award from OSU. Her studies at OSU are being supported in part by a graduate fellowship awarded by the Chinese Scholarship Council. Ting’s current research includes investigations on the effect of consumption of phytochemical-rich red raspberries, omega-3- rich English walnuts, and soy isoflavones. In particular, the work investigates impacts on remediation of symptoms of metabolic disease, and on the gene expression regulation via the activation of hepatic transcription factors including the PPARs, LXR, and HNF-4α.

Patricia M. Guenther, PhD, RD, is a Research Professor in the Division of Nutrition at the University of Utah and Principle Consultant at Guenther Consulting. From 2003 to 2013, she was a nutritionist at the US Department of Agriculture’s Center for Nutrition Policy and Promotion, where conducted research related to dietary assessment and dietary guidelines and supported the development of the 2010 Dietary Guidelines for Americans.

Earlier Dr. Guenther was employed by the USDA Agricultural Research Service, where her work focused on developing improved methods for collecting and analyzing dietary survey data. Dr. Guenther received her B.S. and M.S. degrees in nutrition from Case Western Reserve University in Cleveland, Ohio, and her Ph.D. in Nutritional Sciences from the University of Maryland, College Park. She completed an internship in clinical dietetics at the University of Michigan Medical Center. Dr. Guenther is a registered dietitian, member of the Academy of Nutrition and Dietetics and the American Society for Nutrition, and serves on the editorial board of the Journal of the Academy of Nutrition and Dietetics.

2017 Presentation Title – Blueberries: Is it a “Berry” Good Idea for Cardiovascular Health?

Dr. Stull is an Associate Professor of Nutrition in the Department of Human Ecology at the University of Maryland Eastern Shore. Her research focuses on botanicals and their impact on risk factors associated with metabolic syndrome. Specifically, Dr. Stull’s lab found that supplementation with blueberries for 6 weeks improved insulin sensitivity and endothelial function in adult obese men and women that had metabolic syndrome. Dr. Stull received federal (National Institutes of Health, National Center for Complementary and Integrative Health) and nonprofit (US Highbush Blueberry Council) funding to support her blueberry research. She has published numerous book chapters and manuscripts in peer-reviewed scientific journals related to the health benefits of blueberries. Additionally, she has presented her research findings at many international and national conferences. Dr. Stull is very involved in various professional organizations, such as the American Society for Nutrition (Chair 2013-2014, Young Professional Interest Group; Vice Chair 2015-present, Minority and Diversity Affairs Committee), American Diabetes Association, and NIDDK Network of Minority Health Research Investigators.

Dr. Stull is also a Registered Dietitian and attained her Ph.D. in Nutrition Science from Purdue University. Her graduate training was followed by a National Institutes of Health T32 postdoctoral fellowship in diabetes, nutrition, and botanicals at Pennington Biomedical Research Center (Botanical Dietary Supplements Research Center, Baton Rouge, LA).

During her fellowship, she received the MARC (Maximizing Access to Research Careers) Postdoctoral Professional Development and Enrichment Award. Recently, she was honored as a Diamond of the Department of Nutrition Science at Purdue University. This award recognized her contributions to advancing the field of Nutrition. In her spare time, Dr. Stull enjoys spending time with family and friends, traveling, and scrapbooking.

Presentation

Recovery of Health-Promoting Proanthocyanidins from Berry Co-Products by Alkalization (PDF)

Biography

Dr. Howard received his B.S. degree in Horticulture from Purdue University, and his M.S. and Ph.D. degrees in Food Science from the University of Arkansas. He worked as an Analytical Chemist at the Dole Packaged Foods Research and Development Center for two years, and was an Assistant Professor in the Horticultural Sciences Department at Texas A&M University for five years. He has served on the faculty in the Department of Food Science at the University of Arkansas since 1997.

His research program is focused on the identification and quantification of bioactive compounds in fresh and processed fruits and vegetables. Dr. Howard has published over 70 scientific articles and five book chapters and had delivered over 50 presentations at scientific meetings. He is a Professional Member of the Institute of Food Technologists and the American Chemical Society.

Steven K. Clinton, MD, PhD is the John B. and Jane T. McCoy Chair in Cancer Research at the OSU Comprehensive Cancer Center and a Professor of Internal Medicine in the Division of Medical Oncology at The Ohio State University. He trained for his M.D. and Ph.D. at the University of Illinois in Urban Champaign followed by Internal Medicine internship and residency at the University of Chicago. He proceeded with Medical Oncology training at the Dana-Farber Cancer Institute and Harvard Medical School where he remained on faculty for nearly a decade.

Dr. Clinton joined The Ohio State University in 1998. He is Director of the Prostate and Genitourinary Oncology Program at The James Cancer Hospital and Solove Research Institute. Under his leadership, the clinical program is a national leader in accrual to therapeutic and prevention clinical trials. The program provides integrated multidisciplinary oncology care to patients throughout central Ohio and for national and global referrals.

Dr. Clinton also serves as the Program Leader for Molecular Carcinogenesis and Chemoprevention at The Ohio State University Comprehensive Cancer Center. The focus of this program, involving over 40 faculty, is to elucidate the fundamental mechanisms underlying the development of cancer and to define prevention strategies. A major strength of the program is the “crops to the clinic” research agenda that integrates the efforts of scientists in agriculture, food science, and nutrition with clinical investigators to conduct novel human clinical trials at The James.

Dr. Clinton is very active in bionutrition research at OSU. He serves as Associate Director for the campus wide Center for Advanced Functional Foods Research (CAFFRE) and the OSU Food Innovation Center (FIC), programs dedicated to the development of novel food products and their evaluation for promoting health outcomes and improving global nutrition. He provides service to many national organizations including the American Association for Cancer Research, the American Society of Nutrition, and the American Society for Clinical Oncology.

He recently served the National Academy of Sciences and Institute of Medicine as a member of the Dietary Reference Intake Committee for Vitamin D and Calcium. He is currently serving on the World Cancer Research Foundation / American Institute for Cancer Research (WCRF/AICR) Continuous Update Project committee. He is a member of the Advisory Committee for the United States Department of Health and Human Services and United States Department of Agriculture Dietary Guidelines for America 2015 Report. Dr. Clinton’s research activities focus on many aspects of diet, nutrition, and cancer; primarily focusing upon prostate and other genitourinary cancers. The research efforts include metabolic epidemiology, clinical intervention trials, as well as basic laboratory studies of cellular and molecular biology resulting in over 200 scientific publications, reviews, and book chapters.

John B. and Jane T. McCoy Chair in Cancer Research at OSU Comprehensive Cancer Center Professor of Internal Medicine in the Division of Medical Oncology at The Ohio State University. Director of the Prostate and Genitourinary Oncology Program at The James Cancer Hospital and Solove Research Institute. Program Leader for Molecular Carcinogenesis and Chemoprevention at The Ohio State University Comprehensive Cancer Center. Associate Director for the campus wide Center for Advanced Functional Foods Research (CAFFRE) and the OSU Food Innovation Center (FIC).